Recombinant Human Vascular Endothelial Growth Factor (rh-VEGF)

Product Name: Recombinant Human Vascular Endothelial Growth Factor (rh-VEGF)

Catalog Number: NRPA03S

Packing Details: 2 µg, 10 µg, 100 µg, 1 mg

Formulation: Lyophilized from 20 mM PB, pH 7.4

Mol. Wt.: 20 kDa

Resources: Escherichia coli (E. coli)

Purity: ≥95% by SDS-PAGE analysis

Endotoxin: <1.0 EU/µg protein

Storage Condition: -20oC

Storage Duration: 3 years

EC50: Typically 2~5 ng/ml (Determined by human umbilical vein endothelial cells-HUVECs)

Description:

Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Six forms of human VEGF mRNA encoding VEGF proteins of 121, 145, 165, 183, 189, and 206 amino acids are produced from a single gene as a result of alternative splicing. VEGF165 appears to be the major gene product found in human tissue and is the most effective angiogenic factor in the VEGF family.